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First Human to Sequence DNA in Space: Kate Rubins

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First Human to Sequence DNA in Space: Kate Rubins

In 2016, at 07:36 local time, Kathleen 'Kate' Rubins and her astronaut friends, who arrived at the Baikonur base in Kazakhstan, boarded the newly built Soyuz Spacecraft with the help of an elevator. Their destination would be the International Space Station (ISS), which rapidly orbits our Earth and contributes to space studies. This journey took 2 days.


Kate Rubins, a microbiologist with a PhD in cancer biology from Stanford University, would become the first person to sequence DNA in space. For nearly four months on the space station, he conducted research, including how life in space affects the human body, particularly the skeletal and cardiovascular systems.


Rubins was one of 14 selected from more than 3,500 candidates for NASA's 2009 astronaut training class. Throughout his career, he had served as a highly skilled scientist who helped develop the first smallpox infection model and sought to create therapies for the Ebola and Lassa viruses.


Rubins succeeded in successfully sequencing DNA in microgravity as part of the Biomolecule Sequencer experiment conducted during his four months on the International Space Station. The ability to sequence the DNA of living organisms in space was enough to open up a whole new door to scientific and medical possibilities.

What good will DNA sequencing in space do?


DNA (Deoxyribonucleic Acid) is the building block in an organism on Earth that contains the instructions that its cell must do. These instructions are represented by the letters A, G, C, and T, which represent the four chemical bases of DNA, adenine, guanine, cytosine, and thymine. Both the layout of these base stations can be displayed between placements, these sequences or sequences can be used for a particular organism.


When Rubins could be as it was, being in a place of possible microbial origin in this manned International space or possibly manned International space on Mars, it is likely that those who were there may be suspected of being themselves. So this work is even in a livelihood as an improvement to protect the use of astronauts on long-haul flights.


They sent mouse, virus and bacterial DNA samples to Space to test the making of a DNA called the Biomolecule Sequencer, MinION, created by Oxford Nanopore Technologies. From the vehicle called the minion, the nanopore sends a positive flow through the pores to the so-called membranes, and at the same time, a DNA proximal device passes through. It blocks individual DNA molecules from the nanopores and conforms to a particular DNA sequence in a unique way. By looking at this child, they can identify the specific DNA sequence.


In his interview with this fact, he said, "This was really my dream. How people start their college, real major and real career until the end of high school, which was my short dream."

Rubins can realize his dreams, now he has opened up for us as an eternal being in the world. 


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